Ozempic vs RybelsusPrice & Coverage in Canada
Verified Canadian pharmacy prices for Ozempic and Rybelsus. Updated weekly.
Which is cheaper?
Ozempic
Lowest at Jill Health (Ontario)
Last verified 18 minutes ago · 149 prices tracked · 5 provinces
See all Ozempic prices →Rybelsus
Lowest at Costco Pharmacy (Ontario)
Last verified 18 minutes ago · 98 prices tracked · 4 provinces
See all Rybelsus prices →Side-by-side comparison
About these medications
Ozempic
Ozempic (semaglutide) is a GLP-1 receptor agonist administered as a weekly subcutaneous injection.
Rybelsus
Rybelsus (semaglutide) is a GLP-1 receptor agonist administered as a daily oral tablet.
Related pages
Frequently asked questions
Is Ozempic or Rybelsus cheaper in Canada?
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Both are semaglutide products by Novo Nordisk, but they differ in form and dosage. Ozempic is a weekly injection and Rybelsus is a daily oral tablet, so price comparisons should account for the different supply quantities and dosing schedules. The live prices above show verified Canadian pharmacy prices for each.
Do Ozempic and Rybelsus share the same active ingredient?
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Yes. Both Ozempic and Rybelsus contain semaglutide as the active ingredient and are manufactured by Novo Nordisk. Ozempic is an injectable formulation dosed weekly; Rybelsus is an oral tablet taken daily.
What is the main difference in how Ozempic and Rybelsus are taken?
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Ozempic is administered as a once-weekly subcutaneous injection using a pre-filled pen. Rybelsus is an oral tablet taken once daily. These are distinct Health Canada-approved products with separate product monographs.
Are Ozempic and Rybelsus both covered by provincial drug plans in Canada?
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Coverage depends on your province, insurance plan, and individual criteria. Formulary listings differ between provinces. Check glp1prices.ca/insurance or contact your provincial drug plan for current coverage details.
Is generic semaglutide available as an alternative to Ozempic or Rybelsus?
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Semaglutide's data exclusivity expired January 4, 2026 and generic submissions are pending Health Canada review. Novo Nordisk has also launched Plosbrio (an authorized generic of Ozempic). GLP1Prices.ca tracks pricing for all semaglutide products as they become available.
How often are Ozempic and Rybelsus prices verified on this site?
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Weekly. Each price row shows the date last verified. Prices are shown in Canadian dollars and vary by pharmacy and province.
Health Canada compliance: GLP1Prices.ca displays drug names, prices, and quantities only. We do not make therapeutic claims. This website does not provide medical advice. Consult your healthcare provider about medication options.