MOUNJARO (tirzepatide injection) is indicated for once-weekly administration as an adjunct to diet and exercise to improve glycemic control for the treatment of adult patients with type 2 diabetes mellitus.
About this page. This page summarizes injection technique and storage instructions published by Health Canada in the product monograph for Mounjaro. It is for informational purposes only and is not a substitute for advice from your prescriber or pharmacist. Always follow the instructions provided to you by your healthcare provider. Read our full medical disclaimer →
Prior to initiation of MOUNJARO, train patients on proper injection technique. Advise the patient to carefully read the Instructions for Use included with the Patient Medication Information leaflet before administering the medicinal product.[3]Section 4.4, page 5
MOUNJARO is to be injected subcutaneously in the abdomen, in the thigh, or in the upper arm. Rotate injection sites with each dose.[3]Section 4.4, page 5
Visually inspect MOUNJARO before use. It should appear clear and colourless to slightly yellow. Do not use MOUNJARO if particulate matter or discoloration is seen. MOUNJARO should not be used if it does not appear clear, free of particles, and colourless to slightly yellow. MOUNJARO should not be used if the pen, KwikPen, or vial is damaged. If the pen, KwikPen or vial is dropped on a hard surface, it should not be used.[3]Section 4.4, page 5
MOUNJARO should not be administered intramuscularly or intravenously. When using MOUNJARO with insulin, administer as separate injections and never mix. It is acceptable to inject MOUNJARO and insulin in the same body region, but the injections should not be adjacent to each other.[3]Section 4.4, page 5
Patients using the single-dose vial must be instructed to use a syringe equipped with a needle appropriate for subcutaneous injection (for example, a tuberculin or insulin syringe with a 28- to 31-gauge needle more than 2.1 mm in length that is capable of measuring a 0.5 mL dose volume).[3]Section 4.4, page 5
Store MOUNJARO single-dose prefilled pen and vial in a refrigerator at 2°C to 8°C, up to the expiration date. Do not use MOUNJARO beyond the expiration date. Store MOUNJARO in the original carton to protect from light. Do not freeze MOUNJARO. Do not use MOUNJARO if frozen.[1]Section 11, page 19
If needed, each single-dose pen or vial can be stored unrefrigerated for up to 21 days at temperatures not to exceed 30°C.[1]Section 11, page 19
Store MOUNJARO KwikPen in a refrigerator at 2°C to 8°C up to the expiration date. Do not use MOUNJARO KwikPen beyond the expiration date. Protect MOUNJARO KwikPen from light. Do not freeze MOUNJARO KwikPen. Do not use MOUNJARO KwikPen if frozen.[1]Section 11, page 19
If needed, each multi-dose prefilled KwikPen can be stored unrefrigerated at temperatures not to exceed 30°C for up to 30 days.[1]Section 11, page 19
The single-dose prefilled pen must be discarded after use in a puncture-resistant container. Throw away all opened vials after use, even if there is medicine left in the vial.[1]Section 11, page 19
The MOUNJARO KwikPen must be discarded after four weekly doses in a puncture-resistant container or in accordance with local requirements.[2]Section 11, page 20
Injection technique and storage requirements must be understood in the context of your specific device and medication. Discuss any questions about administration or storage with your prescriber or pharmacist. Use our pharmacy comparison tool to find and connect with a Canadian pharmacy that carries Mounjaro.
Last reviewed May 14, 2026 against the Health Canada Product Monograph dated April 2, 2026. View monograph →