Zepbound Dosing Guide (Canada)
GIP/GLP-1 receptor agonist
About this page. This page summarizes dosing information published by Health Canada in the product monograph for Zepbound. It is for informational purposes only and is not a substitute for advice from your prescriber or pharmacist. Always follow the dosing instructions provided to you by your healthcare provider. Read our full medical disclaimer →
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Titration Schedule
Weeks 1–4
2.5 mg
once weekly
[1]Section 4.2, page 5Initiation dose.
Weeks 5–8
5 mg
once weekly
[1]Section 4.2, page 5Also a recommended maintenance dose per Section 4.2.
Weeks 9–12
7.5 mg
once weekly
[1]Section 4.2, page 5Escalation step; remain ≥ 4 weeks on current dose before increasing.
Weeks 13–16
10 mg
once weekly
[1]Section 4.2, page 5Also a recommended maintenance dose per Section 4.2.
Weeks 17–20
12.5 mg
once weekly
[1]Section 4.2, page 5Escalation step.
Week 21+
15 mg
once weekly
Maximum recommended maintenance dose.
If you miss a dose
If within 4 days
If a dose is missed, administer ZEPBOUND as soon as possible within 4 days (96 hours) after the missed dose. Resume the regular once-weekly dosing schedule.
If outside 4 days
If more than 4 days have passed, skip the missed dose and administer the next dose on the regularly scheduled day. Resume the regular once-weekly dosing schedule.
Talk to your pharmacist or prescriber
Dosing decisions — including when to adjust or maintain your dose — must be made with your prescriber or pharmacist. Use our pharmacy comparison tool to find and connect with a Canadian pharmacy that carries Zepbound.
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Need a prescription? You can get it online
Licensed Canadian practitioners review your case online. Free delivery. $0 consult fee.
Sources
Last reviewed May 14, 2026 against the Health Canada Product Monograph dated April 2, 2026. View monograph →