Zepbound Dosing Guide (Canada)
GIP/GLP-1 receptor agonist
About this page. This page summarizes dosing information published by Health Canada in the product monograph for Zepbound. It is for informational purposes only and is not a substitute for advice from your prescriber or pharmacist. Always follow the dosing instructions provided to you by your healthcare provider. Read our full medical disclaimer →
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Titration Schedule
Weeks 1–4
2.5 mg
once weekly
[1]Section 4.2, page 5Initiation dose.
Weeks 5–8
5 mg
once weekly
[1]Section 4.2, page 5Also a recommended maintenance dose per Section 4.2.
Weeks 9–12
7.5 mg
once weekly
[1]Section 4.2, page 5Escalation step; remain ≥ 4 weeks on current dose before increasing.
Weeks 13–16
10 mg
once weekly
[1]Section 4.2, page 5Also a recommended maintenance dose per Section 4.2.
Weeks 17–20
12.5 mg
once weekly
[1]Section 4.2, page 5Escalation step.
Week 21+
15 mg
once weekly
Maximum recommended maintenance dose.
If you miss a dose
If within 4 days
If a dose is missed, instruct patients to administer ZEPBOUND as soon as possible within 4 days (96 hours) after the missed dose.
If outside 4 days
If more than 4 days have passed, skip the missed dose and administer the next dose on the regularly scheduled day. In each case, patients can then resume their regular once weekly dosing schedule.
Talk to your pharmacist or prescriber
Dosing decisions — including when to adjust or maintain your dose — must be made with your prescriber or pharmacist. Use our pharmacy comparison tool to find and connect with a Canadian pharmacy that carries Zepbound.
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Need a prescription? You can get it online
Licensed Canadian practitioners review your case online. Free delivery. $0 consult fee.
Sources
Last reviewed May 14, 2026 against the Health Canada Product Monograph dated April 2, 2026. View monograph →